Biacna Topical Gel (Clindamycin Phosphate/Tretinoin)

Biacna topical gel (Clindamycin Phosphate/Tretinoin) is a topical prescription medication used to treat severe acne in adults and children over the age of 12. Biacna gel contains two medications, clindamycin and tretinoin. Clindamycin is an antibiotic that works by stopping the growth of bacteria that causes acne. Tretinoin is a form of vitamin A that reduces the amount of oil released by oil glands in your skin, helping your skin renew itself more quickly. The combination gel works by killing bacteria that cause acne and by peeling off skin cells. It may take several weeks to months before you see and improvement in your acne. Use Biacna exactly as prescribed by your doctor. Do not use this medication in larger or smaller amounts, or for longer than recommended. Using more medication or applying it more often than prescribed will not make it work faster, and may increase side effects. Call your doctor if skin irritation becomes severe or if your acne does not improve after several weeks of using this medication.

Manufacturer Information

Common side effects of Biacna include mild skin irritation, dryness, or peeling, mild skin redness, or itching of treated skin. Stop using Biacna gel and call your doctor immediately if you have more serious side effects such as:

• Diarrhea that is watery or bloody;
• Severe redness, burning, stinging, or scaling of treated skin areas

This is not a complete list of side effects and others may occur. Contact your doctor if these side effects worsen or persist, or if you experience any serious side effects not listed above.

You should not use Biacna topical gel if you are allergic to clindamycin or tretinoin, or if you have ever had inflammation of your intestines, Crohn’s disease, ulcerative colitis, or severe diarrhea caused by antibiotic medication. To make sure Biacna is safe for you, tell your doctor if you have a history of stomach or bleeding disorders. Avoid using Biacna gel with other skin medications that contain erythromycin, unless directed by your doctor. Avoid getting Biacna topical gel in your eyes, mouth, or nose (or in the creases of your nose), or on your lips. If it does get into any of these areas, wash with water. Do not apply Biacna to sunburned, windburned, dry, chapped, irritated, or broken skin. It is not known whether Biacna will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether this medication passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine. This medication should not be used on a child younger than 12 years old. It is unlikely that other medications take orally or intravenously will have an effect on topically applied Biacna gel, however it is possible. Tell your doctor about any medications and supplements you are currently taking, or have recently taken, in order to reduce the risk of any interactions.

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